| Date | Location | Result | |
| 03/22/22 | Evansville, Ind. (Ford Center) | Indiana (PA) 67, Hillsdale 55 | Box score |
| 03/15/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 68, California (PA) 59 | Box score |
| 03/13/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 58, Mercyhurst 55 | Box score |
| 03/12/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 65, Fayetteville St. 49 | Box score |
| 03/06/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 63, Millersville 52 | Box score |
| 03/05/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 52, Shippensburg 44 | Box score |
| 03/02/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 70, California (PA) 64 | Box score |
| 02/26/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 72, Pitt.-Johnstown 64 | Box score |
| 02/23/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 81, Clarion 65 | Box score |
| 02/19/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 78, Seton Hill 53 | Box score |
| 02/16/22 | Edinboro, PA | Indiana (PA) 83, Edinboro 71 | Box score |
| 02/12/22 | Erie, PA | Indiana (PA) 77, Gannon 48 | Box score |
| 02/09/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 87, California (PA) 79 | Box score |
| 02/07/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 72, Slippery Rock 61 | Box score |
| 02/05/22 | Slippery Rock, Pa. (Morrow Field House) | Indiana (PA) 70, Slippery Rock 65 | Box score |
| 01/31/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 83, Gannon 50 | Box score |
| 01/29/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 60, Mercyhurst 51 | Box score |
| 01/26/22 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 76, Edinboro 67 | Box score |
| 01/24/22 | Johnstown, Pa. (Sports Center) | Pitt.-Johnstown 70, Indiana (PA) 68 | Box score |
| 01/22/22 | Clarion, Pa. (Tippin Gym) | Indiana (PA) 81, Clarion 47 | Box score |
| 01/19/22 | Greensburg, Pa. (McKenna Center) | Indiana (PA) 100, Seton Hill 60 | Box score |
| 01/12/22 | Erie, Pa. (Mercyhurst Athletic Center) | Indiana (PA) 70, Mercyhurst 67 | Box score |
| 01/08/22 | Lock Haven, Pa. (Thomas Fieldhouse) | Indiana (PA) 79, Lock Haven 72 | Box score |
| 01/05/22 | California, Pa. (Convocation Center) | Indiana (PA) 84, California (PA) 71 | Box score |
| 12/31/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 107, Pitt.-Greensburg 55 | Box score |
| 12/19/21 | Indiana, Pa. (Kovalchick Complex) | Shippensburg 72, Indiana (PA) 60 | Box score |
| 12/18/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 65, Shepherd 46 | Box score |
| 12/14/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 81, Millersville 58 | Box score |
| 12/04/21 | West Chester, Pa. (Hollinger Fieldhouse) | Indiana (PA) 103, West Chester 81 | Box score |
| 12/03/21 | Kutztown, Pa. (Keystone Arena) | Indiana (PA) 86, Kutztown 73 | Box score |
| 11/27/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 97, Virginia St. 45 | Box score |
| 11/19/21 | Bowie, Md. (A.C. Jordan Arena) | Indiana (PA) 90, Bowie State 83 | Box score |
| 11/16/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 106, Le Moyne 67 | Box score |
| 11/13/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 98, Concord 78 | Box score |
| 11/12/21 | Indiana, Pa. (Kovalchick Complex) | Indiana (PA) 87, West Virginia Wesleyan 61 | Box score |